Tuesday, October 25, 2011

Gut Bacteria Influence Statin Action

As increased blood cholesterol levels are considered a huge risk for developing coronary heart disease, it is important to bring down the levels of cholesterol in susceptible people. This can be done through a combination of dietary manipulation and exercise. When these methods do not work out one has to seek the help of medicines. Statins are drugs commonly employed to reduce the blood cholesterol levels. Statins act by blocking the synthesis of cholesterol.
It has however been noticed that the effects of statins vary in different people. Some people respond better than others. It is now revealed that the gut bacteria can influence the effect of statins on human beings. It is already known that the gut bacteria are capable of producing large number of chemicals. Some of these chemicals are beneficial to the host. For example, the gut bacteria can produce vitamin K and vitamin B12 and supply them to the host. Studies have revealed that people in whom the gut bacteria produce three bile acids respond better to the administration of statins.

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